A Physical Model for Regulation-First in the Proto-Liver Origin of Life (PLOL) Framework
Description
The Proto-Liver Origin of Life (PLOL) hypothesis argues that regulation was the first functional step toward life. This companion paper develops a mechanistic model describing how a primitive regulator could naturally arise in prebiotic environments through sunlight-driven redox asymmetry, mineral microcavities, and wet–dry cycling. These structures form energy-buffering microreactors capable of stabilizing electron flow and selecting molecules that improve regulatory control. This regulator-first model provides a physically grounded precursor to metabolism, compartmentalization, and replication, and establishes continuity between geological redox systems and modern hepatic function.
Notes (English)
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A Physical Model for Regulation-First in the Proto-Liver Origin of Life PLOL Framework.pdf
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Additional details
Related works
- Is supplement to
- Preprint: 10.5281/zenodo.17619803 (DOI)
- Preprint: 10.5281/zenodo.17544611 (DOI)
- Preprint: 10.5281/zenodo.17624518 (DOI)
- Preprint: 10.5281/zenodo.17629009 (DOI)
- Preprint: 10.5281/zenodo.17622231 (DOI)
Dates
- Submitted
-
2025-11-18Hypothesis Conceived and published